Carcinogenesis, Teratogenesis & Mutagenesis ›› 2005, Vol. 17 ›› Issue (3): 187-189.doi: 10.3969/j.issn.1004-616x.2005.03.016

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Mutagenicity of the Matter Extracted from the Pulp of Cornus by Ethanol

ZHANG Hui-zhen;SONG Chun-hua;YANG Ji-yao;HU Shi-bin;WU Yi-ming   

  1. Department of Environmental Health, College of Public Health Zhengzhou University,Zhengzhou 450052,Henan,China
  • Received:2004-09-13 Revised:2004-10-28 Online:2005-05-30 Published:2005-05-30
  • Contact: ZHANG Hui-zhen

Abstract: BACKGROUND & AIM: To check the mutagenicity of the matter extracted from the Pulp of cornus by ethanol. MATERIAL AND METHODS: Chromosome aberration test, micronucleus test of bone marrow cell and sperm shape abnormality test in mice were used in this study. RESULTS: The test result shows that: there have no significant difference between the matter extracted from the pulp of cornus by ethanol and negative control, but has significant difference to positive control. CONCLUSION: The matters extracted has no damage effect on the chromosome and cell levels. It provides science proof on exploiting functional health food of cornus of ficinalis sieb.et Zucc.

Key words: pulp of cornus, the matter extracted by ethanol, mutagenicity